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APPLICATIONS: Medical Physics

Mathematical modeling of mitotic cell division at molecular level in order to find new targets for anticancer treatment

Zaharov Pavel
Center for Theoretical Problems of Physicochemical Pharmacology of RAS

DRIVER: Study of molecular mechanisms of protein interactions in mitotic system

STRATEGY: Integration of experimental data from mechano-molecular system of cell division using methods of molecular dynamics and coarse grained models for proteins

OBJECTIVE: Creation new type of anticancer drugs

IMPACT: Scientific: new information about cell division. Commercial: new effective anti-cancer drugs. The market for such medicines is hundreds billions of dollars. Social: increasing length of the life for millions of people

USAGE: Pharmacology, medicine, molecular and cell biology

AREA: Medical Physics, Structure and Dynamics of Atomic-Molecular Systems, Physicochemical Biology